Cards like Disenchant in Fifth Edition:

Divine Offering

Divine Offering

Instant

Destroy target artifact. You gain life equal to its mana value.

5.2 /10
$0.21
Alabaster Potion

Alabaster Potion

Instant

Choose one —
• Target player gains X life.
• Prevent the next X damage that would be dealt to any target this turn.

2.9 /10
$0.23
Sacred Boon

Sacred Boon

Instant

Prevent the next 3 damage that would be dealt to target creature this turn. At the beginning of the next end step, put a +0/+1 counter on that creature for each 1 damage prevented this way.

0.4 /10
$0.16
Blessed Wine

Blessed Wine

Instant

You gain 1 life.
Draw a card at the beginning of the next turn's upkeep.

2.1 /10
$0.20
Eye for an Eye

Eye for an Eye

Instant

The next time a source of your choice would deal damage to you this turn, instead that source deals that much damage to you and Eye for an Eye deals that much damage to that source's controller.

2.9 /10
$0.32
Shield Wall

Shield Wall

Instant

Creatures you control get +0/+2 until end of turn.

2.1 /10
$0.11
Shatter

Shatter

Instant

Destroy target artifact.

5.6 /10
$0.14
Terror

Terror

Instant

Destroy target nonartifact, nonblack creature. It can't be regenerated.

7.3 /10
$0.14
Word of Blasting

Word of Blasting

Instant

Destroy target Wall. It can't be regenerated. Word of Blasting deals damage equal to that Wall's mana value to the Wall's controller.

0.1 /10
$0.19
Enervate

Enervate

Instant

Tap target artifact, creature, or land.
Draw a card at the beginning of the next turn's upkeep.

6.2 /10
$0.24
Hurkyls Recall

Hurkyl's Recall

Instant

Return all artifacts target player owns to their hand.

7.3 /10
$1.81
Blood Lust

Blood Lust

Instant

If target creature has toughness 5 or greater, it gets +4/-4 until end of turn. Otherwise, it gets +4/-X until end of turn, where X is its toughness minus 1.

3.3 /10
$0.18
Boomerang

Boomerang

Instant

Return target permanent to its owner's hand.

7.1 /10
$0.15
Counterspell

Counterspell

Instant

Counter target spell.

10 /10
$1.24
Death Ward

Death Ward

Instant

Regenerate target creature.

3.4 /10
$0.14
Heal

Heal

Instant

Prevent the next 1 damage that would be dealt to any target this turn.
Draw a card at the beginning of the next turn's upkeep.

4.5 /10
$0.20
Healing Salve

Healing Salve

Instant

Choose one —
• Target player gains 3 life.
• Prevent the next 3 damage that would be dealt to any target this turn.

3.1 /10
$0.14
Incinerate

Incinerate

Instant

Incinerate deals 3 damage to any target. A creature dealt damage this way can't be regenerated this turn.

5.9 /10
$0.14
Memory Lapse

Memory Lapse

Instant

Counter target spell. If that spell is countered this way, put it on top of its owner's library instead of into that player's graveyard.

9.1 /10
$0.35
Remove Soul

Remove Soul

Instant

Counter target creature spell.

5.6 /10
$0.12

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